Leveraging Multimodal Profiling of FFPE Tissue to Characterize Disease Biology & Enable Novel Early Target Identification in Crohn’s Disease
Time: 1:35 pm
day: Day One PM
Details:
- Demonstrating how spatial transcriptomics combined with single nuclei RNAseq and multiplex immunofluorescence from FFPE tissue provides a comprehensive view of disease biology, with parallels to immuno-oncology applications
- Showcasing how innovative bioinformatics approaches and histologically guided features can be applied to analyze curated patient cohorts and drive target discovery
- Presenting a novel framework that, while developed for inflammatory diseases, can be adapted to uncover actionable targets in tumor immunology and improve immunotherapy strategies
